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Research in our group lies at the interface of mechano-microbiology and materials-biosystems interactions. We use a multifaceted and integrative approach to quantify, and elucidate the molecular mechanism behind the mechanical forces that stabilize the initial stages of bacterial biofilm formation on different materials. As initial attachment is the crucial pre-requisite for a mature biofilm, initial efforts in the Mechano-microbiology Lab will focus primarily on the early stages of biofilm development―that is initial adhesion and microcolony formation. Below are the key research themes that we are working on (see our Research Page for more details):
- Molecular forces in Bacterial Biofilms―at the single-molecule and single-cell levels
- Bacterial Rigidity Sensing
- Structure and Nanomechanics of Bacterial Biofilms
- Targeted Delivery of Anti-biofilm Agents
Awards and Grants
- Cottrell Faculty Scholar, Class of 2021
- Connaught New Researcher Award
- Alexander von Humboldt Fellowship
- Marcel de Merre Prize in Nanoscience and Nanotechnology
- Andoy, N.M.O., Jeon, K., Kreis, C.T., Sullan, R.M.A. Multifunctional and Stimuli-Responsive Polydopamine Nanoparticle-Based Platform for Targeted Antimicrobial Applications, Advanced Functional Materials, 2020, 2004503.
- Kreis, C.T. and Sullan, R.M.A. Interfacial Nanomechanical Heterogeneity of E. coli Biofilm Matrix, Nanoscale, 2020, 12, 16819–16830.
- Jeon, K., Schmitt, C., Xue, Y., Andoy, N.M.O., Barner, L., Sullan, R.M.A. Size-Controlled Synthesis of Bioinspired Polyserotonin Nanoparticles with Free-Radical Scavenging Property, Journal of Materials Chemistry B, 2021, 9, 634 - 637.
- Falcone, N. Shao, T. Andoy, N.M.O., Rashid, R., Sullan, R.M.A., Sun, X., and Kraatz, H-B. Multi-component Peptide Hydrogels—A Systematic Study Incorporating Biomolecules for the Exploration of Diverse, Tuneable Biomaterials, Biomaterials Science, 2020, 8, 5601–5614.
For more Publication please see: www.sullanlab.com/publications