Carbon Nanotube Conjugates
This project centers on development andapplication ofsensors/electrochemical methods for detection of chemical warfare agent (CWA) mimics. Several different approaches are perused to achievethis goal. 1. ITO electrodes are modified with ferrocene-derivatives or ferrocene-conjugate modified-CNTs Then, electrochemical properties of such modified electrodes (sensors) are characterized. Next, obtained sensors are used to detect chemical warfare agent mimics by employing various electrochemical techniques (e.g. CV, ACV, DPV).2. Ferrocene-amino acid conjugate-modified carbon-nanotubes are used (Fig. below). 3. Another approach involves a ferrocene (Fc) derivative and Ag nanoparticles (NPs). The Boc-protected Fc amino acid derivative is stabilized onto Au through a cystamine linker allowing for deprotection to its active form. Ag NPs are deposited onto substrate in the gas phase forming pristine naked NPs.
Ag nanostructures, shown below, fabricated by the electrochemical cycling of Ag foil under strongly basic conditions were found to be sensitive to the addition of KCN or DECP. This chemsitry is similar to that previously observed to occur in gas-phase Ag nanoparticles deposited onto ITO electrodes. In both systems, a loss of redox activity can be used for the sensitive detection fo cyanide.