My interests lie in the cell biology of human genetic diseases. In particular, I am interested in understanding the mechanisms by which misfolded proteins are dealt with by the cellular quality control and intracellular trafficking machineries in human genetic prion diseases. I am also interested in understanding potential links between protein misfolding disorders such as Alzheimer’s, Huntington and prion diseases.
- genetic disease
- misfolded proteins
- quality control
Research Area: Biochemistry, Cell & Molecular Biology
I am interested in exploring the link between the intracellular accumulation of mutant prion protein and neuronal cell death in specific regions of the brain in human prion diseases.
- BIOB12H: Cell and Molecular Biology Laboratory
- BIOD29H: Pathobiology of Human Disease
- BIOD95H: Supervised Study in Biology (coordinator)
- BIOD98/99Y: Directed Research in Biology (coordinator)