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Professor, Teaching Stream, Associate Chair Teaching and Undergraduate Affairs

Phone: 416-208-5102
Location: SW 521D

Teaching Interests

 

  • BIOD29H: Pathobiology of Human Disease
  • BIOD95H: Supervised Study in Biology (coordinator)
  • BIOD98/99Y: Directed Research in Biology (coordinator)

Research Interests

My interests lie in the cell biology of human genetic diseases. In particular, I am interested in understanding the mechanisms by which misfolded proteins are dealt with by the cellular quality control and intracellular trafficking machineries in human genetic prion diseases. I am also interested in understanding potential links between protein misfolding disorders such as Alzheimer’s, Huntington and prion diseases.

Keywords:

  • genetic disease
  • misfolded proteins
  • quality control
  • prions

Research Area: Biochemistry, Cell & Molecular Biology

Current Research

I am interested in exploring the link between the intracellular accumulation of mutant prion protein and neuronal cell death in specific regions of the brain in human prion diseases.