My interests lie in the cell biology of human genetic diseases. In particular, I am interested in understanding the mechanisms by which misfolded proteins are dealt with by the cellular quality control and intracellular trafficking machineries in human genetic prion diseases. I am also interested in understanding potential links between protein misfolding disorders such as Alzheimer’s, Huntington and prion diseases.
Research Area: Biochemistry, Cell & Molecular Biology
I am interested in exploring the link between the intracellular accumulation of mutant prion protein and neuronal cell death in specific regions of the brain in human prion diseases.