Joanne Nash

 
Joanne Nash

Research Interests: 

My primary research goal is to develop more effective therapies for neurodegenerative and neurological disorders - primarily Parkinson’s disease - so that ultimately, people with these diseases have a better quality of life.  To this end, research in the lab strives to understand how these diseases impact neuronal circuitry, synaptic function and neuronal homeostasis.  As our understanding of the mechanisms underlying these diseases expands, we are beginning to assess novel disease targets and therapies using the most physiologically relevant models and techniques available. 

 

Keywords:

  • Synaptic plasticity
  • Cell death mechanisms
  • Mitochondria
  • Striatum
  • Substantia nigra pars compacta
  • Genetic manipulation
  • Electrophysiology
  • Cell Culture
  • Microscopy
  • Behavioural studies
  • Transgenic mouse
  • Animal models

Research Area: Neurobiology, Parkinson’s disease, Neurophysiology, Neurodegenerative Disease

 

Current Research

  • Understanding pathological synaptic plasticity in Parkinson’s disease.
  • Elucidation of mechanisms linked with neurodegenerative disease.
  • Validation of disease – modifying agents in neurodegenerative disease.

Teaching Interests: 

  • BIOC32H: Human Physiology I
  • BIOD65H: Pathologies of the Nervous System
  • CSB1020H - Current Topics in Neuroscience
  • Neural Plasticity in Neurodegenerative Disease