Clare Hasenkampf

Research Interests

Professor Hasenkampf’s biology research laboratory has been supported by NSERC and has focused on the structure and function of eukaryotic chromosomes, particularly in how the specialized chromosome structures found during meiosis allow homologous chromosomes to come together, recognize each other and undergo reciprocal genetic exchange. The work has focussed on meiosis in commercial & wild cottons, lilies, spiderworts and in the model plant Arabidopsis thaliana. 

Professor Hasenkampf has had a career-long interest in undergraduate education, most especially with finding ways to promote student’s engagement in their education as scientists-in-training (not just as students learning science facts).

Professor Hasenkampf’s efforts as an emeritus professor are in creating educational resources, primarily those relating to meiosis.

Hasenkampf  peer-reviewed research publications

Yisell Farahani-Tafreshi , Chun Wei, Peilu Gan, Jenya Daradur, C. Daniel Riggs, Clare A. Hasenkampf (2022)

The Arabidopsis HOP2 gene has a role in preventing illegitimate connections between nonhomologous chromosome regions. Chromosome Research, DOI 10.1007/s10577-021-09681-2

free access version.  https://rdcu.be/cFtqF

 

Patti E Stronghill, Wajma Azimi and Clare A Hasenkampf (2014) A novel method to follow meiotic progression in Arabidopsis using confocal microscopy and5-ethynyl-2′-deoxyuridine labeling.  Plant Methods 10:33.    secondary author    http://www.plantmethods.com/content/10/1/33

Nazia Pathan, Patti Stronghill, and Clare Hasenkampf (2013) Transmission Electron Microscopy and Serial Reconstructions Reveal Novel Meiotic Phenotypes for the ahp2 Mutant of Arabidopsis thaliana. Genome 56(3):139-145.  10.1139/gen-2012-0157.  joint author

              

de la Paz J, Stronghill P, Douglas S, Saravia S, Hasenkampf C, Riggs D 2012     (Dec) Chromosome fragile sites in Arabidopsis harbor matrix attachment regions and are associated with ancestral chromosome rearrangement events. Plos Genetics 2012;8(12):e1003136  (PGENETICS-D-12-0193) secondary author

 

Teresa Dawson, Sarah Fedko,  Nancy Johnston, Elaine Khoo,  Sarah King,  Saira Mall,  Mary Olaveson, Janice Patterson,  Kamini Persaud,  Frances Sardone, Zohreh Shahbazi, Allyson Skene, Martha Young, and Clare A. Hasenkampf  2010.  Foundation Skills for Scientists: An Evolving Program. 2010.  The Canadian Journal for the Scholarship of Teaching and Learning Volume 1, Issue 1 2010 Article 7 online journal          http://ir.lib.uwo.ca/cjsotl_rcacea/vol1/iss1/   joint author

 

Stronghill, P., Pathan, N., Ha, H., Supijono, E. and C. Hasenkampf. 2010.    Ahp2 (Hop2) function in Arabidopsis thaliana (Ler) is required for stabilization of close alignment and synaptonemal complex formation except for the two short arms that contain nucleolus organizer regions. Chromosoma (2010) 119:443–458. joint author.   

 

Stronghill P. and Hasenkampf, C. 2007. Analysis of substage associations in prophase I of meiosis in floral buds of wild-type Arabidopsis thaliana (Brassicaceae) American Journal of Botany. 94:2063-2067. joint author.

 

Siddiqui, N.S., Hasenkampf, C.A., Rusyniak, S., and Riggs, C.D. (2006) Disruption of the Arabidopsis SMC4 gene, AtCAP-C, compromises gametogenesis and embryogenesis. Planta 223: 990-997. secondary author.

 

Wilson PJ, Riggs, CD and C Hasenkampf. (2005) Plant Chromosome Homology:  Hypotheses Relating Rendezvous, Recognition and Reciprocal Exchange. Cytogenetic Genome Res 109:190-197.  This was both an invited and a peer-reviewed publication.  I was the major author of this paper. primary author.

 

Siddiqui NU, Stronghill P, Dengler RE, Hasenkampf C and Riggs CD. (2003). Mutations in Arabidopsis condensin genes disrupt embryogenesis, meristem organization and segregation of homologous chromosomes during meiosis. Development 130 (14): 3283-95. secondary author.

 

George S, Behl P, deGuzman R, Lee M, Rusyniak R, Hotta Y, Hiratsuka K, Takase H and Hasenkampf, C. (2002) Dmc1 foci in prohase I nuclei of diploid, triploid and hybrid lilies.  Chromosoma 111:96-105.  joint author.

 

Hasenkampf C, Taylor A, Siddiqui N and Riggs CD (2000) Meiotin-1 gene expression in normal anthers and in anthers exhibiting prematurely condensed chromosomes. Genome 43(4): 604-612. primary author.

 

Hasenkampf C, Qureshi M and Rzepczyk A. (1998) Meiotin-1, a meiosis-enriched protein present in normal leptotene chromosomes and lacking in precociously condensed leptotene chromosomes.  Chromosome Research 6: 277-283. primary author.

 

Hasenkampf, Clare A. (1997) A quick, economical and gentle method for applying small volumes of solutions to specimens on glass slides. Microscopy Today 97:20.

 

Taylor A, Horsch A, Rzepczyk A, Hasenkampf C, Riggs CD. (1997) Maturation and secretion of a serine proteinase associated with events of late microsporogenesis. The Plant Journal 12(6): 1261-1271. secondary author.

 

Hasenkampf, CA (1996) The Synaptonemal complex-The chaperone of crossing over?  Chromosome Research 4:133-140.

 

Qureshi M and Hasenkampf CA  (1995) DNA, histone H1 and meiotin-1 immunostaining patterns along whole mount preparations of Lilium longiflorum  pachytene chromosomes. Chromosome Research 3:214-220. joint author.

 

Jayawardene N, Riggs CD, Hasenkampf C (1994) Genome analysis and replication behavior of a set of repetitive sequences of Lilium longiflorum."  Genome 37:535-541. primary author.

 

Hasenkampf CA, Qureshi M, Horsch A, Riggs CD (1992) Temporal and spatial distribution of meiotin-1 in anthers of Lilium longiflorum.   Developmental Genetics 13: 425-434. This was a peer reviewed, invited paper in an issue of the journal devoted to meiosis. joint author.

 

Riggs CD and Hasenkampf CA (1991) Antibodies directed against a meiosis-specific, chromatin-associated protein identify conserved meiotic epitopes. Chromosoma 101: 92-98. joint author

 

Hasenkampf CA (1991) In situ  hybridization of Lilium  whole mount synaptonemal complex preparations.  Journal of Biotechnic and Histochemistry 66: 210-215.

 

Hasenkampf CA (1989) A method for producing syanptonemal complex complements in lily and mouse. J. Heredity 80:197-202.

 

Bates GW, Hasenkampf CA, Contolini CC, Piastuch WC (1987)  Asymmetric hybridization in Nicotiana  by fusion of irradiated protoplasts.  Theoret. and Applied Genetics  74 : 718-726. secondary author.

 

Menzel MY, Hasenkampf CA, Richmond K, Dougherty B (1986) Characteristics of duplications and deficiencies from chromosome translocations in G. hirsutum.  J. Heredity 77: 189-201. secondary author

 

Bates GW,  Hasenkampf CA (1985)  Culture of plant somatic hybrids following electrical fusion. Theoret and Applied Genetics 70 : 227-233. joint author.

 

Hasenkampf CA,  Menzel MY ( 1985) Synaptonemal complex karyotyping of Tradescantia  zygotene nuclei.  Amer J Botany 72: 666-673. primary author.

 

Hasenkampf CA (1984) Longitudinal axis thickenings in whole mount spreads from Tradescantia.  Chromosoma 90: 285-288.

 

Hasenkampf, CA (1984) Synaptonemal complex formation in pollen mother cells of Tradescantia. Chromosoma 90: 275-284.

 

Menzel MY, Hasenkampf CA, Stewart J McD (1982) Incipient genome differentiation in Gossypium. III. Comparison of the chromosomes of G. hirsutum  and Asiatic diploids using heterozygous translocations. Genetics 100: 89-103. secondary author

 

Brown MS, Menzel MY, Hasenkampf CA and Naqi N (1981) Chromosome configurations and orientations in fifty-eight heterozygous translocations in G. hirsutum.  J. Heredity 72 :161-168. secondary author.

 

Hasenkampf CA,  Menzel MY (1980)  Incipient genome differentiation in Gossypium.  II. Comparison of the genomes of  G. hirsutum, G. mustelinum, and G. tomentosum  using eight translocations marking three A genome and nine D genome chromosomes. Genetics 95: 971-983. joint author